View abstract. View abstract. J Altern Complement Med. 17. View abstract. Some medications are moved in and out of cells by pumps. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Liu X, Li X, Li X, et al. J Cardiovasc.Surg (Torino) 2000;41(4):631-632. View abstract. View abstract. 2009;14(1):64-65. Armanini D, De Palo CB, Mattarello MJ, et al. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. J Altern Complement Med 2010;16(10):1065-1071. Planta Med 1983;48(5):38-42. Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. Lancet 1992;340:13-17. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. Sheehan M, Rustin MHA, Atherton DJ, et al. Meng Xiangrui is an academic researcher. . Nat Prod Res 2007;21(14):1234-1241. When eaten in large quantities, black licorice can cause serious health issues. The effect of dong quai on menopausal symptoms is unknown. Lee, S. J., Lee, H. M., Ji, S. T., Lee, S. R., Mar, W., and Gho, Y. S. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. Information from this source is evidence-based and objective, and without commercial influence. View abstract. Chang GH, Lin YS, Hsu KH, et al. J Ethnopharmacol. Clin Pharmacol Ther 1996;59:62-71. Since the content of glycyrrhizin is either decreased or removed from the DGL licorice supplement, its positive effects on PCOS may also be reduced. Zhou Y, Jin L, Kong F, et al. View abstract. J Dermatolog Treat 2003;14(3):153-157. Biofactors 2009;35(1):98-104. Journal of Clinical Therapeutics Medicine. View abstract. 2019;18(Suppl1):291-301. View abstract. View abstract. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. Biol Pharm Bull 2007;30(11):2191-2195. PC-SPES, a dietary supplement for the treatment of hormone-refractory prostate cancer. Am J Chin Med 1992;20(3-4):313-317. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. Sigurjonsdottir HA, Franzson L, Manhem K, et al. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. View abstract. Hypertension encephalopathy after liquorice ingestion. J Clin Psychopharmacol 1997;17(3):234-235. Most clinical trials have found that when Peony is combined with Licorice Rt. Warfarin is used to slow blood clotting. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. Awad N, Makar G, Burroughs V, Ravi P, Burroughs SR. Licorice-induced apparent mineralocorticoid excess causing persistent hypertension and hypokalemia. J Hum Hypertens 2003;17(2):125-131. van Marle J, Aarsen PN, Lind A, van Weeren-Kramer J. Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium. View abstract. J Agric Food Chem 6-13-2007;55(12):4691-4697. Mamgain RK, Gupta M, Mamgain P, et al. J Clin Psychopharmacol 2008;28(3):264-370. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. Drugs & Vitamins . View abstract. Caradonna, P., Gentiloni, N., Servidei, S., Perrone, G. A., Greco, A. V., and Russo, M. A. Am J Chin Med 2003;31:445-53. . Immunology 1997;90(1):115-120. Eur J Dermatol. Report of a new case]. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. Westman EC, Guthrie GP. J Pharmacol Exp Ther 2006;316:1369-77. B. and Tang, T. Q. Rev Med Brux 2008;29(5):490-493. View abstract. Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. [A plant extract and its modified preparation in functional dyspepsia. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. 2017 Sep;31(9):1330-1340. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. View abstract. View abstract. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. 2020;16(3):458-462. Murck H, Lehr L, Hahn J, Braunisch MC, Jezova D, Zavorotnyy M. Adjunct Therapy With Glycyrrhiza Glabra Rapidly Improves Outcome in Depression-A Pilot Study to Support 11-Beta-Hydroxysteroid Dehydrogenase Type 2 Inhibition as a New Target. Akbari N, Asadimehr N, Kiani Z. Effects of the Japanese herbal medicine "Sho-saiko-to" (TJ-9) on in vitro interleukin-10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C. Hepatology 1997;25(6):1390-1397. 2020;45(2):257-264. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . View abstract. Let's take a look at the forms, uses, and side effects of . Migraine. Arch.Pharm Res 2012;35(11):1945-1952. View abstract. van Uum SH. Gulf J Oncolog 2021;1(37):42-47. (Tokyo) 2008;54(3):244-249. Immediately afterwards, Teacher Liu looked at her, picked up her paper, and said, Student Zhou Xiaotong, this time I ll give you a warning. N Engl J Med 1991;325:1223-7. View abstract. Complement Ther Med. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Kumada T, et al. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. Crit Care 2011;15(1):R64. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. . Pharmacol Biochem Behav 1993;45:719-23. . Pseudohyperaldosteronism, liquorice, and hypertension. Klin Wochenschr 1983;61:303-5. Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. Goultschin, J., Palmon, S., Shapira, L., Brayer, L., and Gedalia, I. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori. Ito, M., Nakashima, H., Baba, M., Pauwels, R., De Clercq, E., Shigeta, S., and Yamamoto, N. Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV- III/LAV)]. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. View abstract. View abstract. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Man SC, Li XB, Wang HH, et al. 2004;24(12):1084-1086. Da Nagao, Y., Sata, M., Suzuki, H., Tanikawa, K., Itoh, K., and Kameyama, T. Effectiveness of glycyrrhizin for oral lichen planus in patients with chronic HCV infection. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. View abstract. 17. Zhongguo Zhong.Yao Za Zhi 2009;34(21):2695-2700. Am J Psychiatry 1994;151:617-8. Bruynzeel DP. J Clin Periodontol 1991;18(3):210-212. View abstract. View abstract. Hinoshita F, Ogura Y, Suzuki Y, et al. Am J Nephrol 2000;20:145-8. But I didn't take it long enough to see any change. J Cosmet.Sci 2006;57(1):57-64. Peony might change how quickly the liver breaks down these medications. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. A multicentre trial. Licorice might decrease the effects of warfarin. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. View abstract. A., Motallebnejad, M., and Khanian, M. The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . [Clinical study on effect of recombinant roasted licorice decoction combined with low-dose glucocorticoids in treating idiopathic thrombocytopenic purpura]. [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Lancet 2-10-1979;1(8111):319. Moghadamnia, A. In an ovarietctomized model, oral administration of a combination of white peony and licorice increased DHEA and serum estrogen concentration. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. View abstract. View abstract. J Clin Endocrinol Metab 2003;88:2384-92. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. View abstract. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. Effects of cerebral ischemia-reperfusion on pharmacokinetic fate of paeoniflorin after intravenous administration of Paeoniae Radix extract in rats. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. View abstract. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. View abstract. Mohire, N. C. and Yadav, A. V. Chitosan-based polyherbal toothpaste: as novel oral hygiene product. Fitoterapia 2006;77(7-8):613-614. van den Bosch AE, van der Klooster JM, Zuidgeest DM, et al. Nihon Jinzo Gakkai Shi 2010;52(1):80-85. Am J Respir.Cell Mol.Biol. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. It has an effect similar to aldosterone. B. Licorice-associated reversible cerebral vasoconstriction with PRES. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. View abstract. View abstract. Medicine (Baltimore) 2018;97(11):e0073. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. Das SK, Das V, Gulati AK, and et al. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. Taking licorice with paclitaxel might decrease the effects of paclitaxel. View abstract. Psychoneuroendocrinology. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. Endocrinol Jpn 1991;38(2):167-174. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. N Engl J Med 1999;341:1158. View abstract. View abstract. View abstract. 1991;78(1-2):1-6. Lapi F, Gallo E, Bernasconi S, et al. Licorice might increase blood pressure. 1. Pharm Biol. N Engl J Med 1968;278(25):1381-1383. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Cancer 1997;79(8):1494-1500. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. Am J Chin Med 2001;29(3-4):459-467. Int Urol Nephrol. 2020;50:102401. Phytother Res. It may disrupt the production of sex hormones ( 9 ). Papandreou V, Magiatis P, Chinou I, et al. Licorice is an herb that grows in parts of Europe and Asia. Patients received either bromocriptine 5 mg daily for 4 weeks followed by 4 weeks of 22.5 grams daily of the peony-licorice decoction (equivalent to 25 mg of glycyrrhetinic acid), or the same drugs in the reverse order. Armanini, D., Nacamulli, D., Francini-Pesenti, F., Battagin, G., Ragazzi, E., and Fiore, C. Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application. [Effectiveness of interferon, glycyrrhizin combination therapy in patients with chronic hepatitis C]. Steroids 2005;70(8):538-542. The sweet stuff in your kids' trick-or-treat buckets may come with a bitter side effect. 2020;247:112226. View abstract. Am J Chin Med 2005;33(5):747-758. Cardiovasc.Drugs Ther 1998;12(6):599-600. J Biol Response Mod 1985;4:551-84. J Nutr 2001;131:1471-8. View abstract. They also have a range of other intriguing activities. 2019;35:329-41. (Glycyrrhiza glabra), it performs better, especially for relaxing muscles, reducing painful menstruation, as well as lowering serum and free testosterone levels in women with PCOS. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. View abstract. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. After lab testing, the Cheng team found that Huang Qin Tang had a high inhibitory property against the debilitating side effects of a chemotherapy drug called CPT-11 (later approved as irinotecan), including diarrhea, nausea, and vomiting. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. View abstract. View abstract. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. Select a condition to view a list of vitamins. Ann Clin Biochem 2007;44(Pt 4):397-399. Zhang YD, Lorenzo B, Reidenberg MM. The efficacy of an ayurvedic preparation of yashtimadhu (Glycyrrhiza glabra) on radiation-induced mucositis in head-and-neck cancer patients: A pilot study. Drug Metab Dispos 2015;43(7):1147-53. View abstract. View abstract. Anon. Lee, S., Lim, J. M., Jin, M. H., Park, H. K., Lee, E. J., Kang, S., Kim, Y. S., and Cho, W. G. Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin. View abstract. Liquorice supplements West J Med 1997;167(3):184-185. This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects. View abstract. Suzuki H, Ohta Y, Takino T, and et al. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. Nephron 2002;90:240. Ed. Bell ZW, Canale RE, Bloomer RJ. Ha Y, Wang T, Li J, et al. An Bras Dermatol 2010;85(5):613-620. 10. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. 2020;2020:8401239. It might also decrease the effects of birth control pills. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. J Clin Psychopharmacol 1997;17(3):234-235. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . Koo YK, Kim JM, Koo JY, et al. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. This versatile anti-inflammatory plant can benefit digestive issues, hormone health, and skin health as well as helping ease problems with menstruation and menopause. Maeda T, Shinozuka K, Baba K, et al. Licorice might increase how quickly midazolam is broken down by the body. View abstract. OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. Phytother Res 1988;2(3):140-145. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. View abstract. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. Evid Based Complement Alternat Med 2016;2016:8292486. View abstract. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. View abstract. View abstract. View abstract. View abstract. Iran J Pharm Res. J Clin Psychopharmacol 2008;28(3):264-370. *. Z. View abstract. Phytother Res 2006;20(8):687-695. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Curr.Pharm.Des 2010;16(26):2935-2947. Abe K, Higurashi T, Takahashi M, et al. Immunopharmacology 1999;41(3):169-181. View abstract. J Nutr Sci Vitaminol. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. 2010;16(4):216-218. Taking licorice along with "water pills" might make potassium levels drop too low. Zhong Xi Yi Jie He Za Zhi 1991;11:102-4, 69. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. The 54-year-old man was in a fast food . G Ital Dermatol Venereol 2010;145(6):789-792. The yellow-brown thick-branched roots are used as medicine. Because licorice has a hormone-like effect, it can relieve excessive gastric acid secretion. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. Learn more about Peony health benefits, uses, side effects, effectiveness, safety, precautions, and warnings. View abstract. Taking licorice along with estrogen might decrease the effects of estrogen. October 15, 2021. Qi XG. Results of a double-blind placebo controlled comparative study]. Severe hypokalaemia with paralysis induced by small doses of liquorice. Zhang W, Leonard T, Bath-Hextall F, et al. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. View abstract. Arch Pharm Res 2002;25(3):293-299. View abstract. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. But the potential side effects are real enough. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). View abstract. View abstract. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. View abstract. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). Tewari SN, Wilson AK. Feng Z, Xu J, He G, et al. Phytother Res 2008;22(2):141-148. View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Br Med J 9-17-1977;2(6089):738-739. Helpful. View abstract. Astragalus may interact with medications that suppress the . Burgess, J. Neth J Med 2005;63:119-20. Isr J Dent Sci 1989;2(3):153-157. No side effects or changes in liver function tests occurred during the study. 1988;8(11):660-2, 645. View abstract. 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. Nutrition 2002;18(3):268-273. NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. View abstract. Comparative Study of the Effect of Licorice Muco-adhesive Film on Radiotherapy Induced Oral Mucositis, A Randomized Controlled Clinical Trial. BMJ Case Rep. 2012 Oct 19;2012. 1999;15:499-523. Eur J Pharmacol 11-7-2005;524(1-3):111-119. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. It shows a wide range of biological and pharmacological activities, including anti-inflammatory and immune regulatory actions. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. Yang F, Qi X, Du Y, et al. View abstract. 6 Top Celery Juice Benefits & Side Effects. View abstract. View abstract. Health Care Women Int. Bronson Korean Panax Ginseng 1000 mg Supports Energy, Endurance & Vitality + Memory and Mental Performance, 120 Capsules. View abstract. Some of these health benefits have also . Grebeniuk, V. N., Mannanov, A. M., Korsun, V. F., and Vinogradova, A. I. Nippon Rinsho 1994;52:1817-22. Mol Nutr Food Res 2006;50(11):1080-1086. Food Chem Toxicol 1993;31:303-12. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. View abstract. View abstract. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Mouthwash Containing Glycyrrhiza uralensis Extract for Preventing Dental Caries. Some possible side effects with oral use include rash, itching, nasal symptoms, or stomach discomfort, but these are uncommon. CJEM 2010;12(3):224-225. Licorice consumption and serum testosterone in healthy man. Evid Based Complement Alternat Med 2016;2016:9852793. Contact Dermatitis Due to Paeonia (Peony). Medicinal herbs: modulation of estrogen action. View abstract. View abstract. View abstract. Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Kormann R, Languille E, Amiot HM, Hertig A. Wen Y, Tang Y, Li M, Lai Y. . Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. J Am Coll.Nutr 2007;26(3):209-218. Zhong.Xi.Yi.Jie.He.Za Zhi. J Cancer Res Ther. View abstract. View abstract. View abstract. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! Kamei T, Kumano H, Iwata K, et al. Lee, I. T., Lee, W. J., Tsai, C. M., Su, I. J., Yen, H. T., and Sheu, W. H. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. Evid Based Complement Alternat Med. World J Gastroenterol 2-7-2006;12(5):760-764. Zhong Xi Yi Jie He Za Zhi 1991;11(3):150-2, 133. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. Scand.J Gastroenterol. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. J Hepatol 1994;21:601-9. Yoshino T, Yanagawa T, Watanabe K. Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature review. Sontia B, Mooney J, Gaudet L, Touyz RM. View abstract. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. Practitioner 1973;210:820-3. All rights reserved. Quinkler M, Stewart PM. J Gastroenterol 1996;31(5):691-695. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. BJU Int 2000;85:481-5. View abstract. View abstract. View abstract. Diane Calello, executive medical director of the New Jersey Poison Control Center, based at Rutgers New Jersey Medical School, discusses safe . Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. View abstract. Li C, Wang ZB. Hsu, Y. L., Wu, L. Y., Hou, M. F., Tsai, E. M., Lee, J. N., Liang, H. L., Jong, Y. J., Hung, C. H., and Kuo, P. L. Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway. Biol Pharm Bull 1998;21:1277-81. Dai DW, Singh I, Hershman JM. Peony root might decrease the amount of phenytoin in the body. View abstract. The sweet cake that reaches parts other cakes can't! View abstract. Antiviral Res 1987;7(2):99-107. In some cases, this might change the effects and side effects of a medication. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. The 1:1 of peony and licorice group can significantly reduced the ureteral smooth muscle tension and Christina Loosestrife herb can increase the u reteral tension, but the amount is too large, the mechanism may be related with the diuretic row stone. Low potassium levels can increase the side effects of digoxin. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. Some medications are changed and broken down by the liver. Cinatl J, Morgenstern B, Bauer G, et al. Licorice-induced hypermineralocorticoidism. 2014 Jan;35(1):87-99. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. View abstract. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. The Potential Benefits and Side Effects of the White Peony Root. View abstract. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. View abstract. Zhang W, Dai SM. View abstract. 2020. View abstract. View abstract. Kim YR, Nam SH. Exp Med Surg 1969;27:411-20. Case Rep Emerg Med. QJM 2011;104(12):1093-1095. J Am Soc Nephrol 2002;13(1):191-196. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Z., Zhang, Y. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. A., van Dokkum, W., and Savelkoul, T. J. Glycyrrhizic acid: the assessment of a no effect level. OTHER NAME(S): Acide Glycyrrhizique, Acide Glycyrrhizinique, Alca. View abstract. Hypertension and the cortisol-cortisone shuttle. Licorice reduces body fat mass in obese men and women. Bai, Y. S., Zhou, C. Y., and Wang, J. Q. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Int J Cardiol 2008;124(3):e42-e44. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The effect of a traditional Chinese prescription for a case of lung carcinoma. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. View abstract. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. View abstract.